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Development of long-acting nitrate delivery systems
1Pharmaceutical Research and Development, AB Hässle, Mölndal, Sweden.
European Journal of Clinical Pharmacology
|January 1, 1990
Abstract:
In this paper pharmaceutical and biopharmaceutical aspects on the development of long-acting nitrate delivery systems are reviewed. Basic considerations and requirements are also discussed. Recent product development activities are presented, with an emphasis on nitroglycerin in transdermal form and oral isosorbide-5-mononitrate controlled-release formulations.