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A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure
Published on: November 29, 2018
Resistant hypertension and left ventricular hypertrophy: an overview
Cesare Cuspidi1, Alvaro Vaccarella, Francesca Negri
1Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milano, Italy; Istituto Auxologico Italiano, Milano, Italy. cesare.cuspidi@unimib.it
Journal of the American Society of Hypertension : JASH
|December 7, 2010
Summary
Resistant hypertension (RH) is strongly linked to left ventricular hypertrophy (LVH), affecting over half of patients. Early detection and treatment of LVH in RH are crucial for managing cardiovascular risk.
Area of Science:
- Cardiology
- Hypertension Research
Background:
- Subclinical cardiac damage in resistant hypertension (RH) is not well-documented.
- Left ventricular hypertrophy (LVH) is a key indicator of cardiac damage in hypertensive patients.
Purpose of the Study:
- To review the literature on the association between resistant hypertension and left ventricular hypertrophy.
- To assess the prevalence of LVH in patients with RH and its impact on cardiovascular prognosis.
Main Methods:
- A MEDLINE search was conducted for studies published between December 1, 1989, and July 31, 2010.
- Included were 11 cross-sectional and longitudinal studies with 3325 adult patients with RH.
- Key search terms included "resistant hypertension," "left ventricular hypertrophy," and "cardiac damage."
Main Results:
- Prevalence of echocardiographic LVH in RH patients ranged from 55% to 75%.
- LVH prevalence reached 91% in patients with concomitant electrocardiographic (ECG) LV strain.
- Treatment-induced reduction in ECG-LVH positively impacted cardiovascular prognosis.
Conclusions:
- Resistant hypertension is frequently associated with significant left ventricular hypertrophy.
- Assessing LVH in RH patients is vital for cardiovascular risk stratification and treatment decisions.
- Monitoring LVH during treatment can improve patient outcomes.
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