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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jun 6, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Agreement to detect glaucomatous visual field progression by using three different methods: a multicentre study.

M Iester1, E Capris, F De Feo

  • 1Laboratorio clinico anatomo-funzionale per diagnosi e il trattamento del glaucoma e della malattie neurooftalmologiche, Clinica Oculistica, Department of Neurological Sciences, Ophthalmology, Genetic, University of Genoa, Italy. iester@unige.it

The British Journal of Ophthalmology
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

Expert clinicians showed moderate agreement when assessing visual field (VF) progression using Humphrey Field Analyzer (HFA) printouts, Guided Progression Analysis (GPA), and GPA2. Agreement was highest with GPA2, though differences were not statistically significant.

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Last Updated: Jun 6, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

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Published on: May 25, 2020

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Area of Science:

  • Ophthalmology
  • Clinical Optometry
  • Glaucoma Research

Background:

  • Visual field (VF) testing is crucial for diagnosing and monitoring glaucoma progression.
  • Assessing VF deterioration can be subjective, leading to potential inter-clinician variability.
  • Standardized analysis methods aim to improve the reliability of VF progression assessment.

Purpose of the Study:

  • To evaluate the agreement level among nine clinicians in detecting progressive visual field deterioration.
  • To compare the consistency of three analysis methods: HFA overview printouts (HFA OP), Guided Progression Analysis (GPA), and GPA2.

Main Methods:

  • Nine glaucoma specialists assessed 38 VF series using Humphrey Field Analyzer (HFA) 24-2 SITA Standard.
  • Clinicians utilized HFA OP, GPA, and GPA2 to determine progression status.
  • Weighted kappa statistics were employed to measure intra- and inter-observer agreement.

Main Results:

  • Inter-observer agreement (κ) was 0.65 for HFA OP, 0.54 for GPA, and 0.70 for GPA2.
  • Intra-observer agreement ranged from 0.55 to 0.58 across the different methods.
  • While GPA2 showed the highest agreement, the differences between the methods were not statistically significant.

Conclusions:

  • Moderate agreement exists among expert clinicians when assessing VF progression using HFA OP, GPA, or GPA2.
  • GPA2 demonstrated a trend towards higher agreement, suggesting potential benefits for standardized glaucoma monitoring.
  • Further research may be needed to optimize methods for consistent VF progression assessment.