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Related Experiment Video

Updated: Jun 6, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Global longitudinal strain by speckle tracking for infarct size estimation.

Kim Munk1, Niels Holmark Andersen, Søren Steen Nielsen

  • 1Department of Cardiology, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, DK-8200 Aarhus N, Denmark. kim.munk@ki.au.dk

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
|December 7, 2010
PubMed
Summary

Global longitudinal strain (GLS) offers valuable insights into infarct size (IS) after ST-elevation myocardial infarction (STEMI). Early assessment using GLS provides more precise IS estimation than traditional echocardiographic indices.

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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

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Last Updated: Jun 6, 2026

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Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
07:21

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

Published on: February 12, 2011

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Assessing infarct size (IS) after ST-elevation myocardial infarction (STEMI) is crucial for patient management.
  • Traditional echocardiographic indices like left ventricular ejection fraction (LVEF) have limitations in accurately quantifying IS.
  • Global longitudinal strain (GLS) is an emerging technique that may offer improved accuracy.

Purpose of the Study:

  • To compare the utility of GLS with traditional echocardiographic indices (LVEF, WMSI, ESVI) in estimating IS post-STEMI.
  • To determine the accuracy of GLS in quantifying infarct size at different time points after STEMI.

Main Methods:

  • A study involving 227 STEMI patients with echocardiograms at day 1 and day 30.
  • Myocardial perfusion imaging (MPI) was used as the reference standard for IS assessment at day 30.
  • Linear regression models were employed to estimate IS using echocardiographic parameters.

Main Results:

  • One day after STEMI, GLS was more precise in estimating IS than LVEF and ESVI, and comparable to WMSI.
  • GLS significantly complemented standard echocardiographic parameters in estimating IS on day 1.
  • On day 30, GLS showed comparability with LVEF and ESVI, but WMSI was more precise for IS estimation.

Conclusions:

  • GLS provides additional information for estimating final infarct size one day after STEMI revascularization.
  • Further research is required to ascertain the prognostic implications of GLS in STEMI patients.