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Related Concept Videos

Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Drugs that Destabilize Microtubules01:10

Drugs that Destabilize Microtubules

Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that destabilize and prevent microtubules' polymerization. Both natural and synthetic chemicals can be found under this class of drugs. Vincristine and vinblastine, two vinca alkaloids, and colchicine were among the first to be discovered. These drugs can affect cells in various ways, either by inducing a change in cell morphology, preventing...
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Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Jun 6, 2026

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
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Microspheres in cancer therapy.

M S Rajput1, P Agrawal

  • 1College of Pharmacy, IPS Academy, Rajendra Nagar, A.B. Road, Indore, India. mithun.sgsits@gmail.com

Indian Journal of Cancer
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

Cancer microsphere technology offers targeted drug delivery to maximize therapeutic value while minimizing side effects. This approach overcomes conventional drug limitations for improved cancer treatment outcomes.

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Area of Science:

  • Oncology
  • Pharmaceutical Technology
  • Drug Delivery Systems

Background:

  • Anticancer drugs often lack selectivity, causing severe side effects and limiting cure rates.
  • Conventional drug delivery systems struggle to effectively target abnormal cancer cells.
  • Microsphere technology presents a promising solution for site-specific cancer therapy.

Purpose of the Study:

  • To review the application and effectiveness of microsphere technology in targeted cancer therapy.
  • To explore various microsphere formulations for enhanced cancer treatment.
  • To assess the potential of microspheres in improving therapeutic outcomes and reducing side effects.

Main Methods:

  • Comprehensive literature review using PubMed and Medline databases.
  • Keyword searches focused on cancer microsphere technology and targeted drug delivery.
  • Analysis of existing studies on microsphere formulation and application in various cancers.

Main Results:

  • Microsphere technology enables site-specific drug action, crucial for targeting cancer cells.
  • Formulated microspheres demonstrate potential for maximum therapeutic value.
  • This technology significantly minimizes or negates side effects on normal cells.

Conclusions:

  • Microsphere technology is a key innovation in modern cancer therapy.
  • It offers a viable strategy for targeted drug delivery, enhancing efficacy and patient safety.
  • Further research and development in microsphere formulations can revolutionize cancer treatment.