Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Cardiopulmonary Resuscitation I: Adult01:21

Cardiopulmonary Resuscitation I: Adult

Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Annual Summative Feedback Letters are Associated With Improved End-of-Rotation Surgical Faculty Ratings.

Journal of surgical education·2026
Same author

Surgical Patrescence-The Challenge of Becoming a Surgeon-Parent.

JAMA surgery·2026
Same author

Detection of Swallowed Bolus Transit in the Adult Cervical Esophagus by Transmission-Mode Ultrasound.

OTO open·2026
Same author

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B-Acute Lymphoblastic Leukemia.

Pediatric blood & cancer·2026
Same author

Effectiveness of a digital diabetes self-management education and support program in Vietnamese adults with type 2 diabetes.

Scientific reports·2025
Same author

The influence of biological sex on the metabolic basis of skeletal muscle fatigue in vivo.

The Journal of physiology·2025

Related Experiment Video

Updated: Jun 6, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Published on: June 6, 2011

Colloid normalizes resuscitation ratio in pediatric burns.

Iris Faraklas1, Uyen Lam, Amalia Cochran

  • 1Burn-Trauma Center, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.

Journal of Burn Care & Research : Official Publication of the American Burn Association
|December 7, 2010
PubMed
Summary

Colloid rescue improves fluid resuscitation in burned children when crystalloid alone is insufficient. Albumin addition normalized fluid balance and urine output in pediatric burn shock patients.

More Related Videos

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
07:27

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Published on: August 19, 2020

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Related Experiment Videos

Last Updated: Jun 6, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Published on: June 6, 2011

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
07:27

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Published on: August 19, 2020

Integrated Compensatory Responses in a Human Model of Hemorrhage
07:57

Integrated Compensatory Responses in a Human Model of Hemorrhage

Published on: November 20, 2016

Area of Science:

  • Pediatric Burn Care
  • Trauma and Emergency Medicine
  • Fluid Resuscitation Strategies

Background:

  • Fluid resuscitation in pediatric burn patients is complex due to size and sensitivity to fluid imbalances.
  • Over- or underresuscitation poses significant risks for burned children.
  • A regional burn center utilized colloid rescue within its pediatric resuscitation protocol.

Purpose of the Study:

  • To evaluate the efficacy of colloid supplementation (albumin) in pediatric burn resuscitation.
  • To compare outcomes between patients receiving crystalloid alone versus those receiving colloid rescue.
  • To assess the impact of fluid resuscitation strategies on urine output and hospital stay.

Main Methods:

  • Retrospective review of pediatric patients (≥15% TBSA burns) from 2004-2009.
  • Resuscitation guided by Parkland formula, adjusted for urine output.
  • Patients requiring increased crystalloid received colloid (albumin) supplementation.
  • Hourly input/output (I/O) ratio used to assess fluid resuscitation effectiveness.

Main Results:

  • Albumin group (24 patients) had more inhalation injuries and larger burns than crystalloid-only group (29 patients).
  • Albumin administration normalized escalating I/O ratios in patients receiving colloid.
  • Median resuscitation volume was higher in the albumin group (9.7 ml/kg/%TBSA) vs. crystalloid-only (6.2 ml/kg/%TBSA).
  • Hospital stay was significantly lower for crystalloid-only patients (0.59 days/%TBSA) compared to albumin patients (1.06 days/%TBSA).

Conclusions:

  • Hourly I/O monitoring is crucial for managing fluid demands in pediatric burn shock.
  • Colloid supplementation effectively restores normal urine output in pediatric burn patients.
  • While effective for fluid balance, albumin supplementation was associated with a longer hospital stay.