Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Cardiac Output01:17

Exercise and Cardiac Output

Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be met...
Exercise Stress Test01:26

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Regulation of Heart Rates01:31

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals.

Experimental physiology·2024
Same author

Exercise-induced pain within endurance exercise settings: Definitions, measurement, mechanisms and potential interventions.

Experimental physiology·2024
Same author

Elevated muscle pain induced by a hypertonic saline injection reduces power output independent of physiological changes during fixed perceived effort cycling.

Journal of applied physiology (Bethesda, Md. : 1985)·2024
Same author

Inter-day reliability of heart rate complexity and variability metrics in healthy highly active younger and older adults.

European journal of applied physiology·2023
Same author

Functional threshold power and the (manufactured) critical power controversy.

Journal of sports sciences·2023
Same author

Tramadol is a performance-enhancing drug in highly trained cyclists: a randomized controlled trial.

Journal of applied physiology (Bethesda, Md. : 1985)·2023
Same journal

Are All Exertional Heat Strokes Equal?

Medicine and science in sports and exercise·2026
Same journal

Associations of 24-Hour Accelerometer-Measured Movement Behaviors with Chronic Liver Disease and the Mediating Role of Proteomics and Metabolomics.

Medicine and science in sports and exercise·2026
Same journal

Ultrasound Muscle Thickness Is a Poor Index of Criterion Magnetic Resonance Imaging Measures of Resistance Training-Induced Muscle Growth.

Medicine and science in sports and exercise·2026
Same journal

Heart Rate Variability During Exercise-Heat Stress Following Seven Days of Passive Heat Acclimation in Older Males: A Secondary Analysis.

Medicine and science in sports and exercise·2026
Same journal

Capillary Blood as a Potential New Matrix for the Athlete Biological Passport: A Field-Based Comparison Study.

Medicine and science in sports and exercise·2026
Same journal

Does Mental Fatigue Negatively Impact Physical Performance Fatiguability?

Medicine and science in sports and exercise·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers
09:24

A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers

Published on: January 28, 2020

WITHDRAWN:A New VO2maxProtocolAllowing Self-Pacing in Maximal Incremental Exercise.

Alexis R Mauger1, Nick Sculthorpe

  • 1Department of Sport and Exercise Sciences, University of Bedfordshire, Bedford, UK.

Medicine and Science in Sports and Exercise
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

The new Mauger-Sculthorpe test (MSP) allows self-pacing for a more natural maximal oxygen uptake (VO2max) assessment. This novel protocol resulted in higher VO2max values compared to traditional methods.

More Related Videos

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
08:27

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

Published on: February 22, 2022

Related Experiment Videos

Last Updated: Jun 6, 2026

A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers
09:24

A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers

Published on: January 28, 2020

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
08:27

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

Published on: February 22, 2022

Area of Science:

  • Exercise Physiology
  • Sports Science
  • Cardiorespiratory Fitness

Background:

  • Traditional VO2max protocols face criticism for unnatural exercise conditions and variable results based on duration and intensity.
  • There is a need for VO2max testing methods with greater ecological validity and subject control.

Purpose of the Study:

  • To design and validate a novel VO2max protocol (Mauger-Sculthorpe test - MSP) enabling self-pacing within an incremental structure.
  • To compare VO2max and other physiological responses between the MSP and a traditional VO2max test.

Main Methods:

  • 16 untrained participants underwent both the MSP and a traditional VO2max test in a counter-balanced crossover design.
  • The MSP involved 5 incremental 2-minute stages (10-minute total duration) with self-regulated power output based on target RPE.
  • Physiological variables including VO2max, peak power output, VE, HR, and RER were measured.

Main Results:

  • Participants achieved significantly higher VO2max values (40 ± 10 mL·kg·min) and peak power outputs (273 ± 58 W) with the MSP compared to the traditional test (37 ± 8 mL·kg·min and 238 ± 55 W, respectively).
  • Higher VO2max was observed with the MSP even when a plateau was reached in the traditional test.
  • No significant differences were found in VE, HR, or RER between the two protocols.

Conclusions:

  • The MSP offers a self-paced, closed-loop VO2max assessment that eliminates the need for experimenter-estimated work rates and stage durations.
  • The MSP may elicit higher VO2max values than traditional tests, suggesting its potential as a standardized measure.
  • Further research is recommended to explore the MSP's efficacy and potential adoption as a standard VO2max testing protocol.