Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preliminary Effectiveness of the Comprehensive Oncology Rehabilitation and Exercise (CORE) Clinical Workflow Algorithm on Health Outcomes During Nonmetastatic Breast Cancer Care.

International journal of breast cancer·2026
Same author

De-centering the drug: Violet light and amphotericin B enhance antileishmanial activity through additive and host-directed effects.

Experimental parasitology·2026
Same author

AI in practice: a multilingual survey of 2025 BioHackathon participants.

GigaByte (Hong Kong, China)·2026
Same author

The association of an exercise and rehabilitation clinical workflow algorithm on sedentary behavior and performance status from time of breast cancer diagnosis and throughout care.

Breast cancer research and treatment·2026
Same author

Substrate-driven modulation of interfacial charge transfer dynamics in cobalt phthalocyanine-2D material van der Waals heterostructures.

Nanoscale·2026
Same author

Feasibility and acceptability of the Comprehensive Oncology Rehabilitation and Exercise (CORE) clinical workflow algorithm in patients with newly diagnosed stage I-III breast cancer who undergo surgery as first-line treatment.

Cancer·2025
Same journal

Hepatic Congestion-linked Intrahepatic Biliary Strictures After Living Donor Liver Transplantation.

Transplantation·2026
Same journal

Filtered or Fried? Rethinking Intraoperative Cell Salvage in Liver Transplantation.

Transplantation·2026
Same journal

Simultaneous Liver-kidney Versus Liver Transplantation Categorized by Pretransplant eGFR: Impact of the 2017 OPTN Policy.

Transplantation·2026
Same journal

Preformed Anti-DQ Alpha Donor-specific Antibodies and the Risk of Antibody-mediated Rejection After Kidney Transplantation.

Transplantation·2026
Same journal

People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.

Transplantation·2026
Same journal

IL-1 Receptor Blockade Modulates Inflammation During Sequential Perfusion in Ex Vivo Porcine Kidneys.

Transplantation·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
08:12

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

Compatible-incompatible live donor kidney exchanges.

David Steinberg1

  • 1Section of Medical Ethics, Lahey Clinic, Burlington, MA 01805, USA. david.steinberg@lahey.org

Transplantation
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

Altruistic kidney exchanges, where compatible donor-recipient pairs donate kidneys unnecessarily, can increase organ availability. While some ethicists deem these exchanges morally questionable, others argue they represent moral excellence and should be promoted.

More Related Videos

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

Related Experiment Videos

Last Updated: Jun 6, 2026

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
08:12

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Published on: July 15, 2015

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

Area of Science:

  • Medical Ethics
  • Transplantation Medicine
  • Nephrology

Background:

  • Kidney transplantation is a vital treatment for end-stage renal disease.
  • Kidney paired donation (KPD) programs facilitate transplants between incompatible donor-recipient pairs.
  • Unnecessary participation in KPD by compatible pairs is a debated ethical issue.

Purpose of the Study:

  • To analyze the ethical implications of compatible donor-recipient pairs participating in kidney exchanges.
  • To evaluate the potential benefits of such exchanges in increasing overall organ availability.
  • To present arguments for and against the moral permissibility of these exchanges.

Main Methods:

  • Ethical analysis of utilitarian principles versus deontological concerns in organ donation.
  • Review of existing literature on kidney paired donation and transplant ethics.
  • Argumentative discourse on the moral status of altruistic KPD participation.

Main Results:

  • Compatible pairs participating in kidney exchanges can significantly increase the number of available kidneys for transplantation.
  • Transplant ethicists have raised moral objections to these exchanges, viewing them as inappropriate.
  • An opposing ethical analysis supports these exchanges, highlighting their moral merit and advocating for their encouragement.

Conclusions:

  • The participation of immunologically compatible donor-recipient pairs in kidney exchanges, though unnecessary for them, offers a substantial utilitarian benefit by increasing organ availability.
  • Ethical viewpoints are divided, with some condemning these exchanges and others advocating for their promotion as morally commendable actions.
  • Further ethical deliberation is warranted to reconcile differing perspectives on altruistic kidney exchanges and their role in maximizing transplantation outcomes.