Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...

Endoscopic Procedures II: Colonoscopy

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:

Serum Laboratory Studies, Stool Test, Breath Test

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Differences in T-cell Densities and Neighborhood Patterns in Human Colorectal Adenomas and Sessile Serrated Lesions.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2026

Same author

Differences in T-cell counts and neighborhood patterns in human colorectal adenomas and sessile serrated lesions.

bioRxiv : the preprint server for biology·2026

Same author

Tissue gene expression analysis approach in a context of high technical and biological heterogeneity.

BMC research notes·2025

Same author

Dietary pattern and lifestyle risk factors for sessile serrated precursors to colorectal cancer.

The British journal of nutrition·2025

Same author

Tissue gene expression analysis approach in a context of high technical and biological heterogeneity.

Research square·2025

Same author

Creating a standardized tool for the evaluation and comparison of artificial intelligence-based computer-aided detection programs in colonoscopy: a modified Delphi approach.

Gastrointestinal endoscopy·2024

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Editorial: Detection targets for colonoscopy: from variable detection to validation.

Douglas K Rex, David G Hewett, Dale C Snover

The American Journal of Gastroenterology

|December 7, 2010

Summary

This summary is machine-generated.

Colonoscopy quality varies, impacting adenoma and cancer detection. Serrated lesions may be key to improving colon cancer prevention, especially in the proximal colon.

More Related Videos

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Related Experiment Videos

Last Updated: Jun 6, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Area of Science:

Gastroenterology
Endoscopy
Cancer Prevention

Background:

Adenoma detection rate (ADR) is a recognized benchmark for colonoscopy quality.
Colonoscopy effectiveness in preventing proximal colon cancer is lower than for distal cancer.
Serrated lesions are increasingly recognized as important precursors to colorectal cancer.

Discussion:

Endoscopist variability in detecting serrated lesions mirrors that of adenomas.
Serrated lesions may explain the disparity in colonoscopy's protective effect between proximal and distal colon.
Current colonoscopy quality metrics may not adequately account for serrated lesion detection.

Key Insights:

Detection rates for serrated lesions vary significantly among endoscopists.
Serrated lesions are a potential critical target for improving colonoscopy efficacy.
Focusing on serrated lesion detection could enhance colonoscopy's role in preventing proximal colon cancer.

Outlook:

Further research is needed to standardize serrated lesion detection techniques.
Incorporating serrated lesion detection into quality metrics may improve colon cancer outcomes.
Enhanced training for endoscopists on serrated lesion identification is recommended.