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Updated: Jun 6, 2026
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Concise synthesis of catechin probes enabling analysis and imaging of EGCg
Atsushi Yoshida1, Yasuo Hirooka, Yusuke Sugata
1School of Pharmaceutical Sciences, University of Shizuoka and Global COE Program, 52-1 Yada, Suruga-ku, Shizuoka-shi, Shizuoka 422-8526, Japan.
Abstract:
A concise synthesis of APDOEGCg (3) was accomplished. Due to the reactivity of its amine group, the compound could be easily converted to the fluorescein probe 21 and immunogen probe 22 efficiently. We then demonstrated the usefulness of the probes for imaging studies and the generation of antibodies.
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