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Anionic sites in the myelin sheath as shown by cationized ferritin
S Dolapchieva1, K Ichev, W Ovtscharoff
1Department of Anatomy, Histology and Embryology, Medico-Biological Institute, Medical Academy, Sofia, Bulgaria.
Acta Histochemica
|January 1, 1990
Abstract:
The distribution of anionic sites in the myelin sheath of sciatic nerves of rabbits was studied using cationized ferritin. Ferritin molecules were observed on the cytoplasmic sides of the myelin lamellae stratified in paranodes and Schmidt-Lanterman clefts. In the compact myelin, ferritin molecules have not been found in the tissue sections. They have been observed on membranes of the myelin fraction. The significance of the localization of negatively charged groups on the cytoplasmic side of membranes is discussed.