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Updated: Jun 6, 2026

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
Published on: August 22, 2014
Effects of a single bout of exercise on arterial compliance in older adults
Kevin J Nickel1, Luke S Acree, Andrew W Gardner
1Department of Health and Exercise Science, University of Oklahoma, Norman, USA.
Abstract:
The effects of acute exercise on arterial compliance in older adults are unknown. Large and small arterial compliance were assessed during and 24 hours following a 30-minute bicycle ergometer test and on a nonexercise, control condition. The change in large artery compliance was similar between the exercise and nonexercise conditions (P = 0.876). Small artery compliance during the exercise day was higher than the nonexercise day at 45, 60, and 75 minutes following exercise (P < .001), was 17% higher 30 minutes postexercise than at rest (P < .001), and decreased by 20% between 30 minutes (4.5 ± 0.4 mL/mm Hg × 100) and 120 minutes (3.6 ± 0.3 mL/mm Hg × 100) after exercise (P = .027). The current study shows 30 minutes of moderate-intensity exercise transiently increases small arterial compliance 30 minutes after exercise but does not elicit more sustained increases in either large or small arterial compliance.
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