Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clock mutations alter developmental timing in Drosophila.

C P Kyriacou1, M Oldroyd, J Wood

  • 1Department of Genetics, University of Leicester, U.K.

Heredity
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.

Molecular psychiatry·2011
Same author

Learning and memory mutations impair acoustic priming of mating behaviour in Drosophila.

Nature·2011
Same author

Song rhythms in Drosophila.

Trends in ecology & evolution·2011
Same author

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease.

Cell death and differentiation·2011
Same author

Clinical Lecture on the Proper Choice and Adjustment of Trusses.

British medical journal·2010
Same author

Clinical Lecture on Urinary Fistula of the Penis, Treated by Urethroplasty.

British medical journal·2010
Same journal

Non-coding DNA dynamics and its roles as a physical barrier in genome safeguarding across early development and evolution.

Heredity·2026
Same journal

Landscape genetics of the copal tree, Bursera cuneata (Burseraceae): the key role of the tropical dry forest in shaping connectivity at the regional scale.

Heredity·2026
Same journal

From Paleogene to Anthropocene: phylogeography, geographic patterns of traits, and chronology of evolutionary drivers in northeast Asian anurans.

Heredity·2026
Same journal

It is hard to be small: Inbreeding depression on male breeding success depends on body size in a threatened songbird.

Heredity·2026
Same journal

How precise are mutation rate estimates? Comparison of different approaches to estimate de novo mutation rates.

Heredity·2026
Same journal

Insights from farming Macrocystis pyrifera offshore: phenotypic analysis, genome-wide association studies, genomic selection.

Heredity·2026
See all related articles

Fruit fly development time is influenced by internal biological clocks. Short circadian cycle mutants (pers) develop faster, while long cycle mutants (perL) develop slower than wild-type flies.

Area of Science:

  • Chronobiology
  • Developmental Biology
  • Genetics

Background:

  • Circadian rhythms are endogenous biological clocks regulating daily physiological processes.
  • The period (per) gene in Drosophila melanogaster is crucial for circadian clock function.
  • Understanding the interplay between circadian rhythms and developmental timing is essential.

Purpose of the Study:

  • To investigate the relationship between circadian rhythm length and developmental time in Drosophila melanogaster.
  • To determine if genetic mutations affecting circadian cycles impact the rate of development from egg to adult.

Main Methods:

  • Monitoring developmental time of Drosophila melanogaster period mutants (pers and perL) and wild-type strains.
  • Observing developmental progression under controlled environmental conditions.

Related Experiment Videos

  • Comparing the duration from egg to adult eclosion across different genotypes.

    • Main Results:

    • Drosophila melanogaster mutants with shorter circadian cycles (pers, 19 h) exhibited accelerated development compared to wild-type.
    • Mutants with longer circadian cycles (perL, 28 h) displayed slower development rates than wild-type.
    • Significant differences in developmental timing were observed correlating with circadian period length.

    Conclusions:

    • Endogenous circadian timers play a significant role in regulating the developmental rate of Drosophila melanogaster.
    • Genetic variations influencing circadian rhythms can directly affect life cycle progression.
    • These findings highlight a potential link between internal timekeeping mechanisms and developmental processes.