[The research status and development of noninvasive glucose optical measurements]

Diabetes threatens the health of human beings. Because of the disadvantages of invasive glucose detection, Noninvasive glucose measurement which diabetics press for becomes the hotspot in both domestic and overseas academic circles. But up to now none of the available devices offers enough precision to clinical application. The principle, method, characteristics of optical spectrum measurements and current development at home and abroad are reviewed in the present paper, such as photoacoustic spectroscopy method, Raman spectrometry, fluorescence method, polarimetry, optical coherence tomography and near infrared spectroscopy. Then the problems and technical analysis of noninvasive glucose measurements as well as the development direction are discussed, and the dynamic spectrum is pointed out to be one of the most application prospect methods for noninvasive glucose measurement.