Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Histology of the Large Intestine01:26

Histology of the Large Intestine

The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
Muscles of the Pelvic Floor and Perineum01:26

Muscles of the Pelvic Floor and Perineum

The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...
Peritoneum01:21

Peritoneum

The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Impact of Post-inflammatory Pigment Alteration After Psoriasis: Novel Data from the VISIBLE Study.

Dermatology and therapy·2026
Same author

Guselkumab for Moderate to Severe Scalp Psoriasis Across All Skin Tones: Cohort B of the VISIBLE Randomized Clinical Trial.

JAMA dermatology·2025
Same author

Guselkumab for Moderate to Severe Psoriasis Across All Skin Tones: Cohort A of the VISIBLE Randomized Clinical Trial.

JAMA dermatology·2025
Same author

Real‑World Experience of 1 Year of Tralokinumab Treatment in Adult Patients with Atopic Dermatitis: A Single-Center Retrospective Study.

Dermatology and therapy·2025
Same author

ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part two: treatment.

The British journal of dermatology·2025
Same author

ISCL/EORTC-CLTG/USCLC recommendations for the diagnosis, staging and treatment of early-stage paediatric mycosis fungoides: a modified Delphi consensus. Part one: diagnosis and staging.

The British journal of dermatology·2025
Same journal

Drug-Induced Subacute Cutaneous Lupus Erythematosus Associated with Fenofibrate Lipid Lowering Agent.

Skinmed·2025
Same journal

Racial Disparities in the Management of Atopic Dermatitis: An Analysis of the National Ambulatory Medical Care Survey, 2012-2018.

Skinmed·2025
Same journal

"Pseudo-Chik Sign" Following COVID-19: Pigmentation Hitherto Unreported.

Skinmed·2025
Same journal

Hyperpigmented Scaly Lesions in the Axillae.

Skinmed·2025
Same journal

Sweet Syndrome-Like Disorder Induced by the Oxford-AstraZeneca<sup>®</sup> SARS-CoV-2 Vaccine.

Skinmed·2025
Same journal

Lockdown Lessons from Dermatology Consultations during the COVID-19 Pandemic in a Tertiary Care Center.

Skinmed·2025
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Segmental cutaneous piloleiomyomata.

Robert H Cook-Norris1, Adrian O Rodriguez, Bradley T Kovach

  • 1Department of Dermatology, Mayo Clinic College of Medicine, Rochester, MN, USA.

Skinmed
|December 9, 2010
PubMed
Summary
This summary is machine-generated.

A man experienced chronic, painful skin nodules for 30 years. Biopsy confirmed segmental cutaneous piloleiomyomata, a rare benign smooth muscle tumor.

Related Experiment Videos

Last Updated: Jun 6, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Piloleiomyomata are benign neoplasms arising from smooth muscle.
  • Cutaneous piloleiomyomata can present as solitary or multiple lesions.
  • Segmental distribution suggests a genetic or developmental origin.

Observation:

  • A 60-year-old man presented with a 30-year history of persistent, painful, segmental cutaneous nodules on his right flank.
  • Lesions were exacerbated by touch and emotional stress, unresponsive to capsaicin.
  • Physical examination revealed multiple pink to violaceous, firm, tender nodules (3-7 mm).

Findings:

  • Histopathological examination showed dermal proliferation of spindle-shaped cells.
  • Cells exhibited eosinophilic cytoplasm and blunt-ended nuclei without cytologic atypia.
  • Diagnosis of segmental cutaneous piloleiomyomata was established.

Implications:

  • This case highlights a rare presentation of piloleiomyomata with a long-standing, symptomatic course.
  • Segmental piloleiomyomata may require a different diagnostic and management approach.
  • Understanding the pathogenesis of piloleiomyomata is crucial for future therapeutic strategies.