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Updated: Jun 6, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
The advent of a novel diagnosis: melanoma through the ages
1David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. navid.ezra@ucla.edu
Abstract:
In the 1930s, the risk of contracting melanoma was only 1:1500; however, by 1996 this number had risen to 1:87 and has been increasing ever since. To better understand the nature of melanoma, books, journals, and scholarly literary works were searched and contributors of this disease were studied in greater detail. Antiquity of melanoma is said to be approximately 2400 years old based on observations made on 9 Peruvian Inca mummies in the 1960s that showed apparent signs of melanoma. René Théophile Hyacinthe Laënnec, the inventor of the stethoscope, first described melanoma as a disease entity. William Norris, an English general practitioner, gave the first English language report of this disease. There are many other physicians from France, England, and the United States who had an active role in the discovery of melanoma.
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