Related Experiment Video
Updated: Jun 6, 2026
Using Polystyrene-block-poly(acrylic acid)-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization
Published on: July 9, 2015
Synthesis of poly(methyl methacrylate)-block-poly(L-histidine) and its use as a hybrid silver nanoparticle conjugate
Nam Ho Shin1, Jin Kyu Lee, Haiqing Li
1The WCU Center for Synthetic Polymer Bioconjugate Hybrid Materials, Department of Polymer Science and Engineering, Pusan National University, Busan 609-735, Korea.
Abstract:
Poly[(methyl methacrylate)-block-poly(L-histidine)] (PMMA-b-PHIS) was synthesized by combining atom transfer radical polymerization and living ring-opening polymerization of alpha-amino acid-N-carboxyanhydride. The resulting hybrid block copolymer forms reverse micelles in the mixture solution of water and N,N-dimethylformamide (DMF) and self-assembles into PHIS/PMMA core/shell spheres with controllable size in the range of 80 to 250 nm depending on the micellization temperature. The self-assembly of PMMA-b-PHIS was carried out in H2O/DMF (3/7) mixture in the presence of AgNO3. Reduction of the resulting Ag ions encapsulated inside of the reverse micelles yielded an attractive Ag nanoparticle core/polymer shell conjugate system.
