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Levonorgestrel-releasing intrauterine device.

T Luukkainen1, P Lähteenmäki, J Toivonen

  • 1Department of Medical Chemistry, University of Helsinki, Finland.

Annals of Medicine
|April 1, 1990
PubMed
Summary

This study shows a levonorgestrel-releasing intrauterine device is highly effective for preventing pregnancy. It also reduces menstrual bleeding, pain, and has a low infection rate.

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Area of Science:

  • Reproductive Health
  • Contraception
  • Gynecology

Background:

  • Intrauterine devices (IUDs) are a common form of reversible contraception.
  • Levonorgestrel-releasing intrauterine systems offer hormonal benefits.
  • Long-term clinical data is crucial for evaluating contraceptive efficacy and safety.

Purpose of the Study:

  • To evaluate the long-term effectiveness and safety of a 20 microgram/day levonorgestrel-releasing intrauterine device.
  • To assess the impact of this device on menstrual bleeding, pain, and infection rates.

Main Methods:

  • International clinical study.
  • 15 years of follow-up.
  • Over 8000 woman-years of experience.

Main Results:

  • High effectiveness in preventing unplanned pregnancies.
  • Significant reduction in menstrual bleeding and pain.
  • Low rate of intrauterine infections.

Conclusions:

  • The levonorgestrel-releasing intrauterine device is a safe and highly effective contraceptive option.
  • It offers non-contraceptive benefits such as reduced menstrual blood loss and pain.
  • Long-term data supports its reliability and favorable safety profile.

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