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Related Experiment Videos

Sternal fixation with resorbable suture material.

S M van Sterkenburg1, A Brutel de la Rivière, F E Vermeulen

  • 1Department of Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|January 1, 1990
PubMed
Summary

Absorbable sutures like Polydioxanon (PDS) were tested for sternal closure. A pilot study found 20% of patients experienced complete sternal dehiscence, leading to project abandonment.

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Area of Science:

  • Cardiothoracic Surgery
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Sternal closure is a critical step in cardiothoracic surgery.
  • Traditional sternal closure methods include steel wire and polyester sutures.
  • The use of absorbable sutures for sternal closure remains an area of investigation.

Purpose of the Study:

  • To investigate the applicability of absorbable sutures for sternal closure.
  • To evaluate the performance of heavy braided Polydioxanon (PDS Ethicon) sutures in sternal closure.
  • To compare absorbable sutures with traditional materials like steel wire and braided polyester.

Main Methods:

  • A pilot study was conducted to assess sternal closure techniques.
  • Heavy braided Polydioxanon (PDS Ethicon) sutures were used.

Related Experiment Videos

  • Steel wire and braided polyester sutures were also employed for comparison.
  • Main Results:

    • Complete sternal dehiscence occurred in 2 out of 2 patients (20%) in the pilot study.
    • The observed rate of sternal dehiscence was unacceptably high.
    • The project was terminated due to these adverse outcomes.

    Conclusions:

    • Absorbable sutures, specifically heavy braided Polydioxanon (PDS Ethicon), demonstrated poor performance for sternal closure in this pilot study.
    • The high rate of sternal dehiscence necessitates further research into alternative closure methods.
    • The project was abandoned due to safety concerns and unacceptable complication rates.