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Population trends of recurrent coronary heart disease event rates remain high
Tom G Briffa1, Michael S Hobbs, Andrew Tonkin
1School of Population Health M431, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia. Tom.briffa@uwa.edu.au
Insights
Over 40% of major coronary heart disease (CHD) events occur in individuals with existing CHD. This underscores the critical need for robust secondary prevention strategies to manage this high-risk population.
Area of Science:
- Cardiovascular Epidemiology
- Public Health
- Preventive Cardiology
Background:
- Survivors of nonfatal coronary heart disease (CHD) can benefit from preventive interventions.
- The long-term population impact of these interventions on subsequent major CHD events requires further study.
Purpose of the Study:
- To determine population trends in clinically manifest CHD prevalence.
- To assess the proportion of major CHD events occurring in individuals with established CHD.
Main Methods:
- Utilized a longitudinal, person-based event-linked file of CHD from 1980-2005.
- Identified survivors with established CHD (hospitalized within 15 years).
- Examined CHD death and myocardial infarction rates in populations with and without established CHD.
Main Results:
- Annual age-standardized CHD prevalence in Perth was 8.8% (men) and 4.0% (women).
- Prevalence increased exponentially with age, reaching 42% in men aged 80-84.
- Approximately 43% of all CHD events occurred in individuals with established CHD.
Conclusions:
- Over 40% of major CHD events annually occur in individuals with manifest disease.
- This highlights the critical need for effective secondary prevention systems of care.
Background:
Survivors of nonfatal coronary heart disease (CHD) can reduce their risk of further events by various preventive interventions. The impact of such measures as delivered over 11 years, on population rates of subsequent major CHD events, has not been extensively studied. This study determined population trends in the prevalence of clinically manifest CHD and the proportion of major CHD events that occur in this population.
Methods And Results:
A population longitudinal person-based event-linked file of CHD extracted from State Hospital Morbidity Data and Death Registry for 1980 to 2005 was used to identify, for each year from 1995 to 2005, survivors who had a hospitalization for CHD over the previous 15 years (population with established CHD), and to examine the occurrence of CHD death and hospitalization with a principal diagnosis of myocardial infarction in both populations with and without established CHD. The average annual age-standardized prevalence of CHD in the Perth metropolitan region (population 1.6 million) was 28 373 (8.8%) in men and 14 966 (4.0%) in women. Age-specific prevalence increased exponentially with age, from <1% in 35 to 39 age group to 42% in 80 to 84 age group in men and half that in women. The percentage of total CHD events (n=28 941) that occurred in the population with established CHD was approximately 43% in both men and women, 55% and 51%, respectively, for CHD death and 35% and 36% for nonfatal myocardial infarction.
Conclusions:
More than 40% of major CHD events annually occur in persons with manifest disease, highlighting the imperative to implement systems of care that support effective secondary prevention.
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