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Liver disorders in children
A Mehnaz1, A G Billo, S J Zuberi
1Department of Paediatrics, Civil Hospital, Karachi.
JPMA. the Journal of the Pakistan Medical Association
|March 1, 1990
Insights
Acute viral hepatitis is the most common liver disease in children in Karachi. This study details its frequency, presentation, and outcomes in 300 pediatric patients.
Area of Science:
- Pediatric Hepatology
- Infectious Diseases
Background:
- Liver diseases in children represent a significant health concern.
- Understanding the epidemiology of pediatric liver conditions is crucial for public health initiatives.
Purpose of the Study:
- To determine the most common hepatic ailments in children in Karachi.
- To describe the clinical and biochemical characteristics of pediatric liver diseases.
- To evaluate the outcomes of various liver diseases in pediatric patients.
Main Methods:
- Retrospective analysis of 300 pediatric patients with liver diseases.
- Data collected from two major teaching hospitals in Karachi.
- Inclusion criteria encompassed all diagnosed liver conditions in children.
Main Results:
- Acute viral hepatitis and its sequelae were identified as the most frequent hepatic ailments.
- Detailed frequency, clinical presentation, and biochemical findings were documented.
- Outcomes for children with acute viral hepatitis were analyzed.
Conclusions:
- Acute viral hepatitis is the predominant liver disease among children in Karachi.
- The findings highlight the importance of addressing viral hepatitis in pediatric populations.
- Further research into the management and prevention of pediatric liver diseases is warranted.
Abstract:
Retrospective analysis of 300 children with various liver diseases, seen at two major teaching hospitals of Karachi indicates that acute viral hepatitis and its sequelae are the commonest of all hepatic ailments. Their frequency, clinical presentation, biochemical findings and outcome are presented.