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Extraosseous osteosarcoma in Ibadan: case series over a 20-year period

Temitope O Alonge1, Henry A Obamuyide, Gabriel Olabiyi Ogun

  • 1Consultant Orthopedic Surgeon/Senior Lecturer, Department of Orthopedics and Trauma, University College Hospital, and College of Medicine, University of Ibadan, Ibadan, Nigeria;

Rare Tumors
|December 9, 2010
PubMed

Keywords:
Sub-Saharan Africaextraosseous osteogenic sarcomashistology.

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...