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Related Experiment Video

Updated: Jun 6, 2026

Modified Radical Neck Dissection for Cervical Metastasis
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Modified Radical Neck Dissection for Cervical Metastasis

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[Radical neck dissection in advanced thyroid cancer].

Al Grigorovici1, M Costache, C Velicescu

  • 1Clinica a III-a Chirurgicală, Spitalul "Sf. Spiridon", Iaşi, România. lxndrgrgrvc8@gmail.com

Chirurgia (Bucharest, Romania : 1990)
|December 15, 2010
PubMed
Summary

Total thyroidectomy with radical neck dissection may improve survival for advanced thyroid cancer patients. This surgical approach showed promising results, particularly for papillary thyroid cancer in women over 55.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Endocrinology

Context:

  • Thyroid cancer management involves surgical intervention, with varying approaches debated for optimal outcomes.
  • The study investigates the efficacy of total thyroidectomy combined with radical neck dissection for thyroid malignancies.
  • Data were collected from 189 patients with malignant thyroid disorders between 2000 and 2009.

Purpose:

  • To evaluate the survival and recurrence advantages of total thyroidectomy with radical neck dissection in thyroid cancer.
  • To determine the effectiveness of this surgical strategy for different types and stages of thyroid cancer.
  • To identify patient subgroups that benefit most from this combined surgical approach.

Summary:

  • 164 out of 189 patients had papillary or follicular thyroid cancer, confirmed histopathologically.

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  • 59 patients underwent total thyroidectomy with radical or modified radical neck dissection.
  • Immediate complications included bleeding and recurrent laryngeal nerve injury; late complications involved recurrence within two years.

    • Impact:

    • Total thyroidectomy with radical neck dissection is established as an effective method for advanced thyroid cancer.
    • Papillary thyroid cancer, female gender, and age over 55 were associated with the best outcomes.
    • This approach offers a potential survival and recurrence advantage, guiding treatment decisions for specific patient profiles.