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Related Experiment Video

Updated: Jun 6, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Peripheral ulcerative keratitis triggered by bacterial conjunctivitis.

A Pokharel1, S Subedi, M Bajracharya

  • 1Nepal Eye Hospital, Tripureshwor, Kathmandu, Nepal.

Nepalese Journal of Ophthalmology : a Biannual Peer-Reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

Infections can trigger peripheral ulcerative keratitis (PUK) in patients with rheumatoid arthritis. Prompt treatment with steroids and hydroxychloroquine is crucial for managing this severe eye condition.

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Related Experiment Videos

Last Updated: Jun 6, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
04:48

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Peripheral ulcerative keratitis (PUK) is a severe inflammatory eye condition affecting the cornea.
  • It is characterized by destructive, crescent-shaped inflammation of the perilimbal corneal stroma.

Observation:

  • A case of PUK following acute bacterial conjunctivitis in a 60-year-old female patient is presented.
  • The patient had a two-year history of intermittent joint pain, later diagnosed as rheumatoid arthritis (RA).

Findings:

  • The patient underwent conjunctival resection and received topical and oral steroids for PUK.
  • Hydroxychloroquine was prescribed upon confirmation of rheumatoid arthritis with a positive RA factor.

Implications:

  • This case underscores the critical role of infections as a potential trigger for PUK in individuals with underlying autoimmune conditions like RA.
  • Early recognition and management of both infectious triggers and autoimmune disease are essential for preserving vision in PUK patients.