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Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms
E T Jensen1, A Kharazmi, K Lam
1Department of Clinical Microbiology, Statens Seruminstitut, Copenhagen, Denmark.
Infection and Immunity
|July 1, 1990
Abstract:
The interaction of human neutrophils with Pseudomonas aeruginosa biofilms was examined by using a chemiluminescence assay. The biofilms induced an oxidative burst response by polymorphonuclear leukocytes which was slow and only 25% of the response to planktonic bacteria. The reduced response to P. aeruginosa biofilms could play a role in the persistence of bacteria in chronic infections.