Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbes and Other Elemental Cycles

Microbes and Other Elemental Cycles

Microbial activity plays a pivotal role in the biogeochemical cycling of iron and manganese, especially at the redox gradients characteristic of stratified aquatic environments. These cycles are driven by microbial transformations between oxidized and reduced forms of the metals, allowing organisms to exploit them for metabolic energy and structural purposes.Iron Cycling Across Redox GradientsIn neutral, oxygen-rich surface waters, iron is predominantly found in its oxidized, insoluble ferric...

Vitamins

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

Drug Dosing: Infants and Children

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...

Minerals

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.

The Early Endosome: Endocytosis of Transferrin

The Early Endosome: Endocytosis of Transferrin

Essential proteins such as insulin or low-density lipoprotein (LDL) and micronutrients such as iron enter a eukaryotic cell through receptor-mediated endocytosis. Subsequently, the early endosomes fuse with the vesicles containing such receptor-ligand complexes and play a vital role in sorting the incoming ligands and receptors. While the ligands are either degraded inside the vesicle or released into the cytosol, their receptors are returned to the plasma membrane for further rounds of...

Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neural correlates of mental illness related stigma: a systematic review of neuroimaging evidence.

Journal of psychiatric research·2026

Same author

The INSIDE-OUT longitudinal technique for bladder neck closure in children: A simplified and innovative approach.

Journal of pediatric urology·2026

Same author

Differential connectivity between core hubs underlying demanding executive functions in schizophrenia compared to autism and control adults.

Frontiers in psychiatry·2026

Same author

Evaluation of penoscrotal transposition associated with complex hypospadias and concealed penis: Photographically controlled analysis of surgically treated patients and proposal of a novel classification (The Corrêa-Macedo classification).

Journal of pediatric urology·2026

Same author

A survival curve for bladder function without lower urinary tract reconstruction associated with in-utero myelomeningocele repair: Results from a prospective one-institution analysis since 2011.

Journal of pediatric urology·2026

Same author

Letter to the Editor re: "Ventral flap aided glans urethral disassembly (V-GUD) technique for distal hypospadias".

Journal of pediatric urology·2026

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

[Routine iron supplementation in pregnancy].

António Macedo¹, Sónia Cardoso

¹Serviço de Medicina Geral e Familiar, Centro Saúde Senhora da Hora, Matosinhos.

Acta Medica Portuguesa

|December 15, 2010

Summary

Routine iron supplementation in pregnancy does not improve clinical outcomes for mothers or newborns, despite increasing iron levels. Anemia symptoms during pregnancy warrant individual evaluation for iron needs.

Area of Science:

Obstetrics and Gynecology
Hematology
Public Health

Background:

Iron deficiency anemia is the most common global micronutrient deficiency, disproportionately affecting pregnant women and young children.
It is linked to increased maternal and perinatal morbidity and mortality.
While iron needs rise in pregnancy, the clinical benefits of routine supplementation in uncomplicated cases are debated.

Purpose of the Study:

To evaluate the clinical effects of routine iron supplementation on mothers and newborns in uncomplicated pregnancies.

Main Methods:

A systematic review of electronic databases (Medline, Cochrane Library, etc.) was performed.
Searches included keywords 'iron' and 'pregnancy', with articles published up to August 2008 selected.
The Strength of Recommendation Taxonomy (SORT) was used to assess evidence levels.

More Related Videos

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

Related Experiment Videos

Last Updated: Jun 6, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

Main Results:

Routine iron supplementation maintained or increased blood iron and ferritin levels, reducing anemia.
No significant effects were observed on key clinical outcomes like preterm labor, birthweight, or perinatal mortality.
Undesired side effects were associated with iron supplementation.

Conclusions:

Current evidence does not support routine iron supplementation for all pregnancies.
Individual assessment is recommended for pregnant women exhibiting signs or symptoms of anemia.