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Changes in atrioventricular conduction and predictors of pacemaker need after percutaneous implantation of the
Antonio J Muñoz-García1, José M Hernández-García, Manuel F Jiménez-Navarro
1Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, España. ajmunozgarcia@secardiologia.es
Insights
Percutaneous aortic valve replacement with CoreValve® frequently leads to pacemaker need due to atrioventricular block. Deeper prosthesis implantation in the left ventricular outflow tract predicts this complication, aiding early identification.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Electrophysiology
Background:
- Transcatheter aortic valve implantation (TAVI) is a common procedure for severe aortic stenosis.
- Atrioventricular conduction abnormalities are frequent post-TAVI, but predictors remain unclear.
Purpose of the Study:
- To investigate electrocardiogram (ECG) abnormalities and identify predictors of pacemaker requirement after CoreValve® TAVI.
Main Methods:
- Retrospective analysis of 65 patients undergoing CoreValve® implantation.
- Clinical and ECG parameters were collected.
- Predictors for pacemaker need due to advanced atrioventricular block were analyzed.
Main Results:
- 34.4% of patients required a permanent pacemaker.
- Left bundle branch block occurred in 47.5% of cases.
- Deeper prosthesis implantation depth in the left ventricular outflow tract (LVOT) was the sole predictor (OR 1.9, P< .007).
Conclusions:
- A significant proportion of patients require pacemakers after CoreValve® implantation.
- LVOT implantation depth is a reliable early predictor of pacemaker need.
Introduction And Objectives:
Although changes in atrioventricular conduction frequently occur after percutaneous implantation of an aortic valve prosthesis, little is known about the mechanisms involved or how these changes progress. We investigated ECG abnormalities and predictors of pacemaker need after percutaneous implantation of the CoreValve® aortic valve prosthesis.
Methods:
Between April 2008 and October 2009, 65 patients with symptomatic severe aortic stenosis received a CoreValve® prosthesis. Clinical and ECG parameters were recorded and predictors of pacemaker need due to advanced atrioventricular block were investigated. The analysis excluded three patients because they had pacemakers and a fourth who died during the procedure.
Results:
The patients' mean age was 79 ± 7.8 years and their logistic EuroSCORE was 20 ± 14%. Implantation was successful in 98.4%. After implantation, 47.5% had left bundle branch block and 21 patients (34.4%) required a permanent pacemaker. The need for a pacemaker was associated with a greater depth of prosthesis implantation in the left ventricular outflow tract (LVOT): 13 ± 2.5 mm vs. 8.8 ± 2.8 mm (P< .001). Moreover, depth was the only predictor: odds ratio 1.9, 95% confidence interval 1.19-3.05 (P< .007). A cutpoint of 11.1 mm for the prosthesis depth in the LVOT had a sensitivity of 81% and a specificity of 84.6% for predicting the need for a pacemaker.
Conclusions:
After CoreValve® aortic valve prosthesis implantation, a high percentage of patients needed a permanent pacemaker for advanced atrioventricular block. The only independent predictor was the depth of the prosthesis in the LVOT, which could serve as an early indicator of pacemaker need.
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