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Narcolepsy

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Sleep-Wake Cycles

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Restless Leg Syndrome and Night Terrors

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Related Experiment Video

Updated: Jun 6, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

Published on: November 1, 2015

[Narcolepsy associated with systemic lupus erythematosus].

F Haddad¹, S Anouti, G Maalouly

¹Service de médecine interne, hôpital universitaire Hôtel-Dieu de France, Ashrafieh, Beyrouth, Liban. prfghaddad@yahoo.com

La Revue De Medecine Interne

|December 15, 2010

Summary

This summary is machine-generated.

Narcolepsy, a sleep disorder, can be a rare manifestation of systemic lupus erythematosus (SLE). This case study shows narcolepsy symptoms improved with SLE treatment, suggesting a link between the two conditions.

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Last Updated: Jun 6, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

Published on: November 1, 2015

Polygraphic Recording Procedure for Measuring Sleep in Mice

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

Area of Science:

Neurology
Immunology
Sleep Medicine

Background:

Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse neurologic and psychiatric manifestations.
Narcolepsy is a chronic sleep disorder, often linked to autoimmune processes, but rarely associated with SLE.

Observation:

A 36-year-old woman presented with narcolepsy, characterized by excessive daytime sleepiness.
She later developed diagnosed systemic lupus erythematosus.

Findings:

The patient's narcolepsy symptoms, including excessive daytime sleepiness, resolved following treatment for SLE.
Treatment involved intravenous cyclophosphamide and methylprednisolone, followed by maintenance therapy with hydroxychloroquine, aspirin, and prednisone.

Implications:

Narcolepsy should be considered a potential neuropsychiatric manifestation of systemic lupus erythematosus.
The clinical course of narcolepsy may parallel the activity of systemic lupus erythematosus, highlighting the need for integrated patient management.