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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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Severe lower limb ischemia after bee stings.

Majdi El Husseiny1, Lamisse Karam, Georges Maalouly

  • 1Department of Vascular and Thoracic Surgery, Saint Joseph University, Hôtel Dieu de France Hospital, Beirut, Lebanon. majdi.elhusseiny@gmail.com

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Multiple bee stings caused severe limb ischemia in a healthy man. This rare case highlights delayed, severe allergic reactions to insect bites, emphasizing the need for vigilance.

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Area of Science:

  • Allergy and Immunology
  • Vascular Medicine
  • Toxicology

Background:

  • Bee stings can trigger allergic reactions, ranging from local swelling to life-threatening anaphylaxis.
  • Delayed hypersensitivity reactions following insect bites are documented but uncommon.
  • Ischemia, a condition of inadequate blood supply, can have various causes, including vascular events.

Observation:

  • A case study of a previously healthy male patient who experienced multiple bee stings.
  • The patient presented with severe ischemia affecting the left lower limb.
  • No prior medical history of allergies or vascular conditions was reported.

Findings:

  • The severe ischemia of the left lower limb was directly linked to the bee stings.
  • This suggests a potential delayed or severe allergic/inflammatory response triggered by the venom.
  • The case illustrates an unusual and severe vascular complication following bee envenomation.

Implications:

  • Highlights the potential for severe, delayed vascular complications from bee stings, even in healthy individuals.
  • Underscores the importance of considering insect sting reactions in the differential diagnosis of acute limb ischemia.
  • Suggests further investigation into the mechanisms underlying venom-induced vascular compromise.