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Updated: Jun 6, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

Left ventricular hypertrophy causes different changes in longitudinal, radial, and circumferential mechanics in

Hidemichi Kouzu1, Satoshi Yuda, Atsuko Muranaka

  • 1Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan. kouzu@sapmed.ac.jp

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|December 15, 2010
PubMed

Insights

Hypertension can impair heart function. This study shows that while radial systolic function may initially increase, hypertrophic remodeling leads to reduced radial function and hidden longitudinal systolic dysfunction in hypertensive patients.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Hypertension Research

Background:

  • Systolic reserve is a key compensatory mechanism for the heart facing increased afterload.
  • Longitudinal systolic dysfunction is known in hypertensive hearts, but radial and circumferential function require further investigation.
  • Left ventricular geometry plays a crucial role in cardiac function and adaptation to hypertension.

Purpose of the Study:

  • To investigate three-directional systolic function in asymptomatic hypertensive patients.
  • To examine the relationship between systolic function and left ventricular geometry.
  • To utilize two-dimensional speckle-tracking imaging for detailed functional analysis.

Main Methods:

  • Echocardiographic evaluations were conducted on 74 hypertensive patients and 55 age-matched controls.
  • Two-dimensional speckle-tracking imaging was employed to assess systolic function.
  • Left ventricular geometry was analyzed in relation to systolic performance.

Main Results:

  • Longitudinal strain was significantly reduced in hypertensive patients with concentric and eccentric hypertrophy compared to controls.
  • Radial strain was elevated in hypertensive patients with normal geometry but attenuated in those with other geometric patterns.
  • These findings suggest a complex interplay between cardiac remodeling and systolic function in hypertension.

Conclusions:

  • Hypertrophic remodeling negatively impacts the compensatory increase in radial systolic function.
  • Latent longitudinal systolic dysfunction is associated with altered left ventricular geometry in hypertensive individuals.
  • These results highlight the importance of assessing multi-directional systolic function in hypertensive heart disease.
Abstract

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