Related Experiment Video
Updated: Sep 11, 2026
09:57
System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
[Determination of the sensitivity of tuberculosis bacteria to pyrazinamide using human macrophage culture]
1Webb-Waring Lung Institute, University of Colorado Health Sciences Center, Denver.
Pneumologie (Stuttgart, Germany)
|February 1, 1990
Abstract:
Increasing interest is being shown in the antituberculous drug pyrazinamide. An in-vitro model using cultures of human blood macrophages was tested with 8 different Mycobacterium tuberculosis trains. A good correlation was found between the susceptibility of the strains to pyrazinamide and the Kinetics in the macrophage culture.
