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Updated: Jun 6, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Coexistence of epileptic encephalopathy with continuous spike-and-wave during sleep, atypical benign partial
Imad Yassin Saadeldin1, Saeed M Al-Tala
1Department of Pediatrics, Armed Forces Hospital, Southern Region, Khamis Mushayt, Saudi Arabia. eysaad@yahoo.co.uk
Abstract:
Epileptic encephalopathy with continuous spike-and-wave during sleep is a rare age-related childhood encephalopathy characterized by neuropsychological and motor impairment, epilepsy, and typical EEG findings. Fixation-off sensitivity denotes forms of epilepsy and/or EEG abnormalities that occur during eye closure. The authors describe a girl with developmental regression, electrical status epilepticus during sleep (documented by video/EEG recording), and intermittent myoclonus. Her younger brother was diagnosed with atypical benign partial epilepsy, and his repeated video/EEG recordings unexpectedly showed fixation-off sensitivity.
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