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[Aging changes in ocular tissues and their influences on accommodative functions].

S Nishida1

  • 1Dept. of Opthalmol., Aichi Medical Univ., Japan.

Nippon Ganka Gakkai Zasshi
|February 1, 1990
PubMed
Summary
This summary is machine-generated.

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As people age, their ability to focus (accommodation) declines due to changes in the crystalline lens and ciliary muscle. This study investigated these age-related morphological changes in the lens and their impact on accommodative amplitude.

Area of Science:

  • Ophthalmology
  • Biophysics
  • Gerontology

Context:

  • Age-related decline in the amplitude of accommodation is well-documented.
  • The specific morphological changes in the crystalline lens and ciliary muscle contributing to this decline are not fully understood.

Purpose:

  • To investigate the age-dependent morphological changes in the crystalline lens and ciliary muscle.
  • To correlate these structural changes with the deterioration of accommodative amplitude.

Summary:

  • Both subjective and objective accommodative amplitudes decrease with age, with objective measurements consistently lower.
  • The crystalline lens increases in thickness with age and accommodative effort, with reduced elasticity in older individuals.
  • Scanning electron microscopy revealed age-related irregularities in crystalline lens fiber substructures, suggesting early cataractous changes.

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Impact:

  • Provides insights into the structural basis of presbyopia.
  • Highlights age-related alterations in lens morphology and cell surface structures.
  • Suggests potential links between lens structural changes and reduced accommodative function.