Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glycoproteins from the aorta.

M Moczar, E Moczar

    Pathologie-Biologie
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    This review explores aortic glycoproteins, detailing their isolation, structure, properties, and biological roles. Structural glycoproteins, distinct from soluble forms, associate with the collagen-elastin matrix and play a role in morphogenesis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of an alpha-blocker (Nicergoline) and of a beta-blocker (Acebutolol) on the in vitro biosynthesis of vascular extracellular matrix.

    Pathologie-biologie·2001
    Same author

    Pseudointima in inflow and outflow conduits of a left ventricular assist system: possible role in clinical outcome.

    ASAIO journal (American Society for Artificial Internal Organs : 1992)·2001
    Same author

    Effect of variation in systemic blood flow on plasma TNF-alpha in a pig model with left ventricular assist device.

    Artificial organs·2001
    Same author

    Intestinal tissue oxygenation and tumor necrosis factor-alpha release during systemic blood flow changes in pigs with left ventricular assist devices.

    Artificial organs·2001
    Same author

    New agents for the treatment of infarcted myocardium.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2000
    Same author

    Structural changes in porcine bioprosthetic valves of a left ventricular assist system in human patients.

    The Journal of heart valve disease·2000
    Same journal

    Pathologie-biologie·2020
    Same journal

    Antibacterial and antibiofilm activities of Laurus nobilis L. essential oil against Staphylococcus aureus strains associated with oral infections.

    Pathologie-biologie·2015
    Same journal

    [Not Available].

    Pathologie-biologie·2015
    Same journal

    Oxidative damage and histopathological changes in lung of rat chronically exposed to nicotine alone or associated to ethanol.

    Pathologie-biologie·2015
    Same journal

    Biological diagnosis of diabetes mellitus.

    Pathologie-biologie·2015
    Same journal

    Association of CagPAI integrity with severeness of Helicobacter pylori infection in patients with gastritis.

    Pathologie-biologie·2015
    See all related articles

    Area of Science:

    • Biochemistry
    • Cell Biology
    • Connective Tissue Research

    Background:

    • Aortic glycoproteins are crucial components of the extracellular matrix.
    • Understanding their properties is key to comprehending vascular health and disease.

    Purpose of the Study:

    • To review isolation techniques, structure, physicochemical properties, and biological functions of aortic glycoproteins.
    • To differentiate between soluble and structural aortic glycoproteins.

    Main Methods:

    • Isolation of glycoproteins using varying ionic strengths and buffers.
    • Characterization of molecular weights and amino acid composition.
    • In vitro biosynthesis studies using aortic smooth muscle cells.
    • Electron microscopy for structural analysis.

    Related Experiment Videos

    Main Results:

    • Two distinct types of glycoproteins identified: soluble and structural.
    • Structural glycoproteins are associated with the collagen-elastin matrix and form microfibrils.
    • Molecular weights range from 27,000-72,000 daltons.
    • Aortic glycoproteins are rich in polar amino acids.
    • Biosynthesis by aortic smooth muscle cells confirmed.
    • Glycoprotein-elastin interactions suggested in morphogenesis.

    Conclusions:

    • Aortic glycoproteins exhibit distinct immunological and structural properties.
    • Structural glycoproteins are integral to the aortic extracellular matrix.
    • Glycoprotein-elastin interactions are implicated in tissue morphogenesis.