Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cystic Fibrosis: Management

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Oral Melanoma: A South American Collaborative Series of 21 Cases.

Head and neck pathology·2026

Same author

Combination therapy overcomes secondary PARPi resistance in ATM-deficient prostate cancer.

NPJ precision oncology·2025

Same author

Clinical and epidemiological profile of oral squamous cell carcinoma in young adults: a multicentric study in Argentina.

Oral surgery, oral medicine, oral pathology and oral radiology·2025

Same author

Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study.

Oral diseases·2023

Same author

Oxidative dissolution mechanism of both undoped and Gd<sub>2</sub>O<sub>3</sub>-doped UO<sub>2</sub>(s) at alkaline to hyperalkaline pH.

Dalton transactions (Cambridge, England : 2003)·2023

Same author

Correction to: Characterization of Alu and recombination-associated motifs mediating a large homozygous SPG7 gene rearrangement causing hereditary spastic paraplegia.

Neurogenetics·2021

Same journal

Hepatic steatosis in adults on CFTR modulators is commonly associated with cardiometabolic criteria consistent with metabolic dysfunction-associated steatotic liver disease.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Same journal

Real-time breath metabolomics to assess early response to CFTR modulators in adults with cystic fibrosis: An open-label proof-of-concept study.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Same journal

Cystic fibrosis nutrition: Addressing emerging trends following the 2024 ESPEN-ESPGHAN-ECFS guidelines. Expert opinion recommendations.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Same journal

Healthcare priorities and needs for LGBTQIA+ people with cystic fibrosis: A concept mapping study.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Same journal

Persistence of large P. aeruginosa aggregates despite reduced airway burden in people with cystic fibrosis on CFTR modulator therapy.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

Same journal

Partnership between cystic fibrosis centres in Europe: The Twinning Project.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 15, 2026

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Published on: February 11, 2017

Optimizing strategies for CFTR molecular testing

Javier Gimenez, Maria D Ramos, Teresa Casals

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society

|December 15, 2010

Summary

No abstract available in PubMed .

More Related Videos

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Published on: March 9, 2015

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Published on: May 10, 2014

Related Experiment Videos

Last Updated: Jan 15, 2026

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Forskolin-induced Swelling in Intestinal Organoids: An In Vitro Assay for Assessing Drug Response in Cystic Fibrosis Patients

Published on: February 11, 2017

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Published on: March 9, 2015

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Published on: May 10, 2014