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Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus
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Vancomycin-related eosinophilic peritonitis.

Mitchell H Rosner1, Bed Chhatkuli

  • 1Division of Nephrology, University of Virginia Health System, Charlottesville, Virginia, USA. mhr9r@virginia.edu

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

Eosinophilic peritonitis (EP) can be a rare complication of peritoneal dialysis. This case highlights intraperitoneal vancomycin as a potential cause of EP, even with negative cultures.

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Eosinophilic peritonitis (EP) is a known complication of peritoneal dialysis (PD).
  • EP is typically linked to dialysis system components, solutions, or infections.
  • Previous reports have associated EP with icodextrin use in PD.

Observation:

  • A case of EP developed in a patient undergoing PD.
  • The patient was treated with intraperitoneal vancomycin for peritonitis caused by methicillin-resistant Staphylococcus epidermidis.
  • Peripheral eosinophilia was noted concurrently.

Findings:

  • The patient's EP resolved after discontinuing vancomycin.
  • Cultures for bacteria and fungi were negative, ruling out common infectious causes.
  • Causation was inferred from the temporal relationship, eosinophilia, and resolution upon vancomycin cessation.

Implications:

  • Vancomycin allergy should be considered in the differential diagnosis of EP in PD patients.
  • Thorough investigation, including negative cultures, is crucial for diagnosing EP.
  • This case expands the understanding of potential iatrogenic causes of EP in PD.