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Oral treatment for Mycobacterium ulcerans infection: results from a pilot study in Benin
Annick Chauty1, Marie-Françoise Ardant, Laurent Marsollier
1Centre de Diagnostic et de Traitement de l'Ulcère de Buruli, Pobè, Bénin.
Abstract:
Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chemotherapy using rifampicin plus clarithromycin during an 8-week period. The treatment was well tolerated, and all patients were healed by 12 months after initiation of therapy without relapse.
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