Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Local Anesthetics: Adverse Effects

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...

Peripheral Artery Disease IV: Nursing Management

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Transversus abdominis plane block in renal allotransplant recipients: A retrospective chart review.

Saudi journal of anaesthesia·2016

Same author

EVALUATION, FEEDBACK AND REMEDIATION IN ANESTHESIOLOGY RESIDENCY TRAINING: A SURVEY OF 124 UNITED STATES PROGRAMS.

The journal of education in perioperative medicine : JEPM·2016

Same author

Intraneural injections and regional anesthesia: the known and the unknown.

Minerva anestesiologica·2011

Same author

Ultrasound-guided interscalene catheters performed under general anesthesia in a patient with Huntington's disease.

Minerva anestesiologica·2010

Same author

Delayed diagnosis of posterior reversible encephalopathy syndrome (PRES) in a parturient with preeclampsia after inadvertent dural puncture.

International journal of obstetric anesthesia·2007

Same author

Unintentional transfixation of a transverse cervical vein during placement of an interscalene brachial plexus catheter.

Journal of clinical anesthesia·2000

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Published on: November 21, 2025

Complications of peripheral nerve blocks.

C L Jeng¹, T M Torrillo, M A Rosenblatt

¹Department of Anaesthesiology, Mount Sinai School of Medicine, New York, USA.

British Journal of Anaesthesia

|December 15, 2010

Summary

Peripheral nerve blocks are generally safe, but serious complications like nerve injury and local anesthetic systemic toxicity can occur. This review covers current knowledge on these rare but significant risks.

Area of Science:

Anesthesiology
Neurology
Pain Management

Background:

Peripheral nerve blocks are widely used for surgical anesthesia and analgesia.
While generally safe, complications can have severe consequences for patients and clinicians.

Purpose of the Study:

To review current knowledge on peripheral nerve injury from nerve blocks.
To discuss complications associated with continuous peripheral nerve catheter techniques.
To cover local anesthetic systemic toxicity (LAST).

Main Methods:

Literature review of peripheral nerve block complications.
Synthesis of data on nerve injury, catheter techniques, and LAST.
Focus on current understanding and clinical implications.

More Related Videos

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Jun 6, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Published on: November 21, 2025

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Main Results:

Peripheral nerve injury is a rare but serious complication.
Continuous catheter techniques present specific risks.
Local anesthetic systemic toxicity (LAST) is a critical concern.

Conclusions:

Awareness and understanding of potential complications are crucial for safe practice.
Minimizing risks involves proper technique and vigilance for systemic toxicity.
Further research can refine safety protocols for nerve blocks.