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Related Concept Videos

Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...

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Updated: Jun 6, 2026

Swine Model of Biofilm Infection and Invisible Wounds
07:16

Swine Model of Biofilm Infection and Invisible Wounds

Published on: June 16, 2023

Infection in conflict wounded.

W G P Eardley1, K V Brown, T J Bonner

  • 1Academic Department of Military Trauma and Surgery, Royal Centre for Defence Medicine, Academic and Research Directorate, West Wing, Institute of Research and Development, Vincent Drive, Birmingham B15 2SQ, UK.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

Infection remains a significant challenge in military medicine, despite advances in trauma care. Understanding the history of war wound infections is crucial for managing current and future combat casualties.

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Area of Science:

  • Military medicine
  • Infectious diseases
  • Trauma surgery

Background:

  • Historically, wound management focused on suppuration, hindering progress.
  • Microscopy and improved sanitation revolutionized understanding and treatment of war wound infections.

Observation:

  • Modern military medicine has improved survivability through rapid evacuation and advanced surgical interventions.
  • Infectious complications are a major concern for surviving combatants.

Findings:

  • The evolution of microbial flora in war wounds presents an ongoing challenge.
  • Antibiotic use, nosocomial transmission, and infectious sequelae require continued clinical focus.

Implications:

  • Effective management of combat wound infections is critical for military healthcare systems.
  • Research into infection control and treatment is a priority, especially with high rates of extremity injuries.