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Updated: Jun 6, 2026

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
Published on: October 22, 2019
Efficacy of a new oxygenator-integrated fat and leukocyte removal device
Andrea Dell'Amore1, Alberto Tripodi, Andrea Cavallucci
1Department of Cardiovascular Surgery, Villa Maria Cecilia GVM Hospital for Care and Research, Cotignola, Lugo, RA, Italy. dellamore76@libero.it
Abstract:
We evaluated the effectiveness of a new oxygenator-integrated device for removing lipid particles and leukocytes from shed mediastinal blood in 20 patients undergoing elective cardiac surgery under cardiopulmonary bypass. Another 20 patients undergoing cardiac surgery without the device served as controls. After filtration with the RemoveLL device, lipid particles, leukocytes, and fats were significantly reduced compared to preoperative levels. In the control group, blood fats and lipid particles at the end of cardiopulmonary bypass were significantly increased compared to preoperative levels. Leukocyte counts at the end of bypass were significantly lower in patients who had the filtration device compared to the control group. Platelets counts and hematocrit changes were not significantly different between the 2 groups.
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