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Related Concept Videos

Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

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Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
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Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots

Published on: June 2, 2015

Developing research programs in clinical and translational nutrition.

Frederick A Moore1, Thomas R Ziegler, Daren K Heyland

  • 1Department of Surgery, Weill Cornell Medical College, Houston, TX, USA. famoore@tmhs.org

JPEN. Journal of Parenteral and Enteral Nutrition
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

Improving nutrition support therapy in hospitalized patients requires more research. Strategies include increased funding, training for young physicians, and collaboration between nutrition and medical societies for larger studies.

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Area of Science:

  • Clinical Nutrition
  • Medical Research
  • Translational Science

Background:

  • Clinicians recognize the benefits of nutrition support therapy for hospitalized patients.
  • Optimal nutrition management is currently underutilized in clinical practice.
  • A deficit in high-quality research hinders widespread adoption of nutrition support.

Purpose of the Study:

  • To identify key strategies for enhancing clinical nutrition research.
  • To address the need for more robust evidence in nutrition support therapy.
  • To propose actionable steps for advancing nutrition research in medical settings.

Main Methods:

  • Discussion of three primary strategies to boost nutrition research activity.
  • Emphasis on increasing research funding and training opportunities.
  • Advocacy for collaboration between national nutrition and medical/surgical societies.

Main Results:

  • Identified strategies focus on financial support, professional development, and community engagement.
  • Proposed partnerships aim to facilitate larger-scale clinical and translational research programs.
  • The article outlines a pathway to strengthen the evidence base for nutrition support.

Conclusions:

  • Enhanced funding, training, and researcher engagement are crucial for advancing clinical nutrition.
  • Collaborative efforts between nutrition and medical specialties are essential for impactful research.
  • Strengthening research infrastructure will improve the implementation of nutrition support therapy.