Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Optical coherence tomography alone is insufficient for glaucoma management.

Indian journal of ophthalmology·2026

Same author

Spontaneous Amsler's sign.

Oman journal of ophthalmology·2024

Same author

Effect of topical brinzolamide on visual function and waveform in patients of infantile nystagmus syndrome: A randomized control trial.

Indian journal of ophthalmology·2024

Same author

Evaluation of Visual Cortex Activity Using Functional Near-Infrared Spectroscopy in Primary Open Angle and Primary Angle Closure Glaucoma: A Pilot Study.

Journal of glaucoma·2024

Same author

Changes in confocal microscopy in glaucoma patients after intraocular pressure reduction with medical therapy.

Indian journal of ophthalmology·2024

Same author

Efficacy of Micropulse Laser Cyclophotocoagulation Therapy in Primary Angle Closure Glaucoma.

Journal of glaucoma·2024

Search research articles

Related Experiment Videos

An Indian perspective on primary angle closure and glaucoma.

Ramanjit Sihota¹

¹Dr RP Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India. rjsihota@hotmail.com

Indian Journal of Ophthalmology

|December 15, 2010

Summary

Primary angle closure disease is common in India, affecting nearly half of adult glaucoma cases. Management involves iridotomy and intraocular pressure control for effective treatment.

Related Experiment Videos

Area of Science:

Ophthalmology
Glaucoma Research

Background:

Primary angle closure disease (PACD) is a significant cause of adult primary glaucoma in India.
Anatomical factors like reduced corneal diameter and anterior chamber depth are noted in PACD patients.

Purpose of the Study:

To summarize primary angle closure disease in India.
To review Indian studies on primary angle closure disease.

Main Methods:

Review of existing Indian studies on primary angle closure disease.
Analysis of anatomical factors, management strategies, and disease progression.

Main Results:

Primary angle closure glaucoma constitutes nearly 50% of adult primary glaucomas in Indian hospitals.
Iridotomy controlled intraocular pressure in 66.7% of subacute and 12.9% of acute cases.
Latanoprost demonstrated greater IOP reduction compared to timolol; disease progression observed over 5 years.

Conclusions:

Primary angle closure disease is prevalent in India.
Effective management is achievable with iridotomy and appropriate intraocular pressure control.