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Mycosubtilins B and C: minor antibiotics from mycosubtilin-producer Bacillus subtilis
1Laboratoire de Biochemie Microbienne (CNRS URA 1176), Université Claude Bernard, Lyon, France.
Microbios
|January 1, 1990
Abstract:
Mycosubtilins B and C were isolated from the culture medium of Bacillus subtilis. The acid hydrolysates of these new antifungal antibiotics, like mycosubtilin, contain alpha-amino acids (Asp3, Glu1, Pro1, Ser1 and Tyr1) and a mixture of iso-C16, n-C16, iso-C17 and anteiso-C17 beta-amino acids. Mycosubtilins B and C differ by the presence of a carboxyl group and of a carboxymethyl group, respectively, instead of a carboxamide group in previously described mycosubtilin.