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Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Related Experiment Video

Updated: Jun 6, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Action and Object Naming in Physiological Aging: An rTMS Study.

Maria Cotelli1, Rosa Manenti, Sandra Rosini

  • 1Istituto Di Ricovero e Cura a Carattere Scientifico, Centro San Giovanni di Dio Fatebenefratelli Brescia, Italy.

Frontiers in Aging Neuroscience
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

High-frequency repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) in older adults sped up action naming. This brain stimulation technique did not affect naming accuracy in healthy aging individuals.

Keywords:
HAROLDbrain stimulationnaming

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Related Experiment Videos

Last Updated: Jun 6, 2026

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Published on: February 14, 2014

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Published on: October 25, 2019

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
13:35

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Published on: April 27, 2014

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Gerontology

Background:

  • Word-retrieval difficulties are common in healthy aging.
  • Repetitive transcranial magnetic stimulation (rTMS) has shown promise in improving picture naming in younger adults and neurological patients.

Purpose of the Study:

  • To investigate the effect of high-frequency rTMS on picture naming in healthy older adults.
  • To assess the impact of rTMS applied to the dorsolateral prefrontal cortex (DLPFC) on naming latency and correctness.

Main Methods:

  • High-frequency rTMS was applied to the left and right DLPFC in 13 healthy older adults.
  • Participants performed object and action naming tasks.
  • Sham stimulation was used as a control.

Main Results:

  • Naming latency for actions was significantly reduced after stimulation of both left and right DLPFC compared to sham stimulation.
  • No significant effect on the correctness of naming was observed.

Conclusions:

  • The findings suggest that both left and right DLPFC are involved in action naming in healthy aging.
  • High-frequency rTMS to the DLPFC can enhance naming speed in older adults.
  • The study discusses the bilateral involvement of DLPFC in aging, referencing data from younger adults and Alzheimer's patients.