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Published on: October 22, 2014

Alcohol consumption and ankle-to-brachial index: results from the Cardiovascular Risk Survey

Xiang Xie1, Yi-Tong Ma, Yi-Ning Yang

  • 1Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.

Plos One
|December 15, 2010
PubMed

Insights

In Chinese men, moderate alcohol intake (under 60g/d) inversely correlates with peripheral artery disease (PAD), while heavy drinking (>60g/d) increases PAD risk. This study clarifies alcohol

Area of Science:

  • Cardiovascular Health
  • Epidemiology
  • Public Health

Background:

  • Low ankle-brachial index (ABI) is a significant indicator of cardiovascular disease and mortality.
  • The association between alcohol consumption and ABI requires further investigation.
  • The Cardiovascular Risk Survey (CRS) provides data on cardiovascular health in diverse Chinese populations.

Purpose of the Study:

  • To investigate the relationship between alcohol consumption and ABI.
  • To determine if alcohol intake is associated with peripheral artery disease (PAD).
  • To analyze these associations across different levels of alcohol consumption in Chinese adults.

Main Methods:

  • Cross-sectional study of 14,618 Chinese adults aged 35+.
  • Data collected from Oct. 2007 to March 2010.
  • Analysis of covariance and multivariable regressions used to assess alcohol intake and ABI relationship.

Main Results:

  • In men, alcohol consumption showed a significant association with ABI (P<0.001).
  • Higher alcohol intake (>60 g/d) was linked to significantly increased odds of PAD in men.
  • Moderate alcohol intake (20.1-60.0 g/d) was associated with significantly lower odds of PAD in men compared to non-drinkers.
  • No significant association between alcohol consumption and ABI or PAD was found in women.

Conclusions:

  • Alcohol consumption is associated with peripheral artery disease in Chinese men.
  • Consumption below 60 g/d showed an inverse association with peripheral atherosclerosis.
  • Consumption of 60 g/d or more showed a positive association with peripheral atherosclerosis in men.
Abstract

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