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More accurate insight into the incidence of human rabies in developing countries through validated laboratory

Laurent Dacheux1, Supaporn Wacharapluesadee, Thiravat Hemachudha

  • 1Institut Pasteur, Dynamics and Host Adaptation Unit, National Reference Centre for Rabies, WHO Collaborative Centre for Reference and Research on Rabies, Paris, France. laurent.dacheux@pasteur.fr

Plos Neglected Tropical Diseases
|December 15, 2010
PubMed
Abstract

No abstract available in PubMed .

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Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...