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Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
Published on: January 7, 2014
Parkinson's disease: is it a toxic syndrome?
Seham A Gad Elhak1, Abdel Aziz A Ghanem, Hassan Abdelghaffar
1Toxicology Department, Faculty of Medicine, Mansoura University, Mansoura 35111, Egypt.
Abstract:
Parkinson's disease (PD) is one of the neurodegenerative diseases which we can by certainty identify its pathology, however, this confidence disappeares when talking about the cause. A long history of trials, suggestions, and theories tried linking PD to a specific causation. In this paper, a new suggestion is trying to find its way, could it be toxicology? Can we-in the future-look to PD as an occupational disease, in fact, many clues point to the possible toxic responsibility-either total or partial-in causing this disease. Searching for possible toxic causes for PD would help in designing perfect toxic models in animals.
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