[Factor VIII-associated antigen/factor VIII ratio in pregnant patients with and without hypertension]

During pregnancy there is an elevation of factor VIII. In hypertensive pregnancy this increase may be smaller. On the other hand factor VIII associated antigen-factor VIII-ratio is said to be increased in these women compared with normotensive ones. There is a discussions about using these change for early detection of PIH. Estimations of factor VIII have been made chemically. Estimations of factor VIII associated antigen have been carried out immunologically. Factor VIII associated antigen-factor VIII-ratio was higher in pregnant women with hypertension than in normotensive ones.