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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein
Jaswinder Sharma1, Hsin-Chih Yeh, Hyojong Yoo
1MPA-CINT, Mail Stop, K771, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Chemical Communications (Cambridge, England)
|December 15, 2010
Abstract:
We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.
