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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

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Related Experiment Video

Updated: Jun 6, 2026

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Efficient Isolation of Adipose-derived Stem Cells and Adipocytes from Porcine Adipose Tissue

Published on: May 26, 2026

Human adipose-derived stem cells: current challenges and clinical perspectives.

Samira Yarak¹, Oswaldo Keith Okamoto

¹Universidade Federal do Vale do São Francisco, Brazil. sa.la@terra.com.br

Anais Brasileiros De Dermatologia

|December 15, 2010

Summary

Adipose tissue-derived stem cells offer regenerative potential. Standardizing methods for isolating and handling these cells is crucial for advancing their clinical applications in regenerative medicine.

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Published on: December 30, 2021

Area of Science:

Regenerative Medicine
Stem Cell Biology

Background:

Mesenchymal stem cells are key for tissue regeneration.
Adipose tissue-derived stem cells (ADSCs) offer advantages over bone marrow mesenchymal stem cells due to less invasive harvesting.
ADSCs exhibit multipotency, differentiating into mesodermal and non-mesodermal lineages.

Purpose of the Study:

To review current methods in adipose tissue-derived stem cell research.
To discuss strategies for future applications in regenerative medicine.
To highlight challenges in obtaining clinical-grade ADSCs.

Main Methods:

Review of existing literature on ADSC isolation, characterization, and handling.
Emphasis on methods relevant to regenerative medicine applications.
Discussion of strategies for standardization and quality control.

Main Results:

Inconsistencies exist in current ADSC research methodologies.
Standardized protocols are needed for reliable clinical-grade cell production.
ADSCs show promise for diverse therapeutic applications.

Conclusions:

Standardized methods are essential for the clinical translation of ADSCs.
Further research is required to overcome challenges in ADSC isolation and application.
ADSCs represent a promising cell source for regenerative medicine.